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Friday, May 15, 2020 | History

4 edition of Genetic dissection of complex traits found in the catalog.

Genetic dissection of complex traits

Genetic dissection of complex traits

  • 276 Want to read
  • 18 Currently reading

Published by Academic Press in San Diego .
Written in English

    Subjects:
  • Morton, Newton E. -- 1929-,
  • Medical genetics,
  • Genetic epidemiology

  • Edition Notes

    Statementedited by D.C. Rao, Michael A. Province.
    SeriesAdvances in genetics -- v. 42
    ContributionsRao, D. C., Province, Michael Arthur.
    The Physical Object
    Paginationxxi, 583 p. :
    Number of Pages583
    ID Numbers
    Open LibraryOL15483396M
    ISBN 100120176424
    OCLC/WorldCa45178874

    Genetic Dissection of Complex Traits with Chromosome Substitution Strains of Mice of CSSs to dissect genetic factors affecting 53 complex traits, 24 in females and 29 in males, related to sterol levels, diet-induced obesity, anxiety, and amino acid levels. Phenotypic.   In the past 10 years, contemporary geneticists using new molecular tools have been able to resolve complex traits into individual genetic components and describe each such component in detail. Molecular Dissection of Complex Traits summarizes the state of the art in molecular analysis of complex traits (QTL mapping), placing new developments in thiCited by:

    Genetic Dissection of Complex Traits is a selection of independent chapters, rather than a systematic introduction to genetic epidemiology. It is organized in 32 chapters that are grouped in nine sections. The first section and the Appendix review Newton Morton's contributions to genetic epidemiology. Section 2 provides background material. Chapter 14 Complex Genetic Interactions (pages –): William K. Scott and Joellen M. Schildkraut Chapter 15 Genomics and Bioinformatics (pages –): Judith E. Stenger and Simon G. Gregory Chapter 16 Designing a Study for Identifying Genes in Complex Traits (pages –): Jonathan L. Haines and Margaret A. Pericak?Vance.

      Chao, H., Wang, H., Wang, X. et al. Genetic dissection of seed oil and protein content and identification of networks associated with oil content in Brassica napus. Sci Rep 7, (). https Cited by: Dissecting the genetics of complex traits using summary association statistics Bogdan Pasaniuc 1 and Alkes L. Price 2,3 Abstract | During the past decade, genome-wide association studies (GWAS) have been used to successfully identify tens of thousands of .


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Genetic dissection of complex traits Download PDF EPUB FB2

Genetic Dissection of Complex Traits is a selection of independent chapters, rather than a systematic introduction to genetic epidemiology. It is organized in 32 chapters that are grouped in nine sections.

The first section and the Appendix review Newton Morton's contributions to genetic epidemiology. Section 2 provides background by: 1. Get this from a library. Genetic dissection of complex traits. [D C Rao; Michael Arthur Province;] -- "This volume presents a long-awaited collection of state-of-the-art methods and strategies for the genetic dissection of complex human diseases and disease-related risk factors.

Written by the. ISBN: OCLC Number: Description: xxvii, pages: illustrations ; 24 cm. Contents: 1. An overview of the genetic dissection of complex traits / D.C. Rao Familial resemblance and heritability / Treva K. Rice Linkage and association: basic concepts / Ingrid B.

Borecki and Michael A. Province Definition of phenotype / Mary K. Wojczynski and. "Genetic Dissection of Complex Traits provides an extensive overview of contemporary methods for statistical gene mapping." Alexandre A.

Todorov for AMERICAN JOURNAL OF HUMAN GENETICS (July ) From the Back Cover. This volume presents a long-awaited collection of state-of-the-art methods and strategies for the genetic dissection of complex Format: Hardcover.

Receive an update when the latest chapters in this book series are published. Sign in to set up alerts. select article Contributors to Volume 60 An Overview of the Genetic Dissection of Complex Traits. D.C. Rao. Pages Download PDF. select article Characterization of LD Structures and the Utility of HapMap in Genetic Association.

Genetic Dissection of Complex Traits (Advances in Genetics Book 60) - Kindle edition by D. Rao, C. Charles Gu. Download it once and read it on your Kindle device, PC, phones or tablets. Use features like bookmarks, note taking and highlighting while reading Genetic Dissection of Complex Traits (Advances in Genetics Book 60).

In the past 10 years, contemporary geneticists using new molecular tools have been able to resolve complex traits into individual genetic components and describe each such component in detail.

Molecular Dissection of Complex Traits summarizes the state of the art in molecular analysis of complex traits (QTL mapping), placing new developments in. Product Information. Genetic Dissection of Complex Traits will present the full range of methodologies that are essential for understanding the basis of human genetic disorders, the origin of such diseases, and theories on how to determine one's genetic predisposition to certain genetic diseases.

Genetic Dissection of Complex Traits Rao Table of Contents Contributors. Preface. Acknowledgments. NEWTON MORTON'S CONTRIBUTIONS Newton Morton: The Wisconsin : Michael Province. Book Description. In the past 10 years, contemporary geneticists using new molecular tools have been able to resolve complex traits into individual genetic components and describe each such component in detail.

Molecular Dissection of Complex Traits summarizes the state of the art in molecular analysis of complex traits (QTL mapping), placing. Most diseases and traits, however, do not follow simple inheritance patterns.

Genetics have thus begun taking up the even greater challenge of the genetic dissection of complex traits. Four major approaches have been developed: linkage analysis, allele-sharing methods, association studies, and polygenic analysis of experimental by: Genetic Dissection of Complex Traits will present the full range of methodologies that are essential for understanding the basis of human genetic disorders, the origin of such diseases, and theories on how to determine one's genetic predisposition to certain genetic diseases.

Medical books Genetic Dissection of Complex Traits, Volume Genetic Dissection of Complex Traits provides an extensive overview of contemporary methods for statistical gene mapping. It is definitely not intended to be a cookbook. Rather, it aims to provide balanced views of the merits and weaknesses of various methods, as a way to promote further discussion.

The book includes discussions of model-based and model-free linkage analysis, candidate gene Cited by: 1. Purchase Genetic Dissection of Complex Traits, Volume 42 - 1st Edition.

Print Book & E-Book. ISBNBook Edition: 1. Read Book Genetic Dissection of Complex Traits, Vol Second Edition (Advances in Genetics). Investigating the genetic basis of complex traits and diseases using individual-level genetic data from genome-wide association studies is often hampered by privacy concerns and logistical Cited by: It is long noted that the genetic component of complex traits is oligogenic (a few genes, each with moderate effects) or even polygenic (many genes, each with small effects) [].

Considering the. Review "Genetic Dissection of Complex Traits provides an extensive overview of contemporary methods for statistical gene mapping." Alexandre A. Todorov for AMERICAN JOURNAL OF HUMAN GENETICS (July ) Synopsis.

Genetic Dissection of Complex Traits will present the full range of methodologies that are essential for understanding the basis of human genetic disorders, the Format: Hardcover. Dissecting the genetics of complex traits using summary association statistics Bogdan Pasaniuc1,2 and Alkes L.

Price3,4,5 1. Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California Los Angeles 2. Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles by: 4.

Most diseases and traits, however, do not follow simple inheritance patterns. Geneticists have thus begun taking up the even greater challenge of the genetic dissection of complex traits. Four major approaches have been developed: linkage analysis, allele-sharing methods, association studies, and polygenic analysis of experimental : Eric S.

Lander, Nicholas J. Schork. In the early days of complex trait genetics, the mids, the candidate gene approach was widely used. This approach evaluates whether common variations of biochemically defined candidate genes are associated with a particular disease by evaluating the frequency of various alleles in case versus control populations (Table ).One of the first important examples was the gene for.Title: Genetic Dissection of Complex Traits In Silico: Approaches, Problems and Solutions VOLUME: 1 ISSUE: 3 Author(s):Jing Hua Zhao and Qihua Tan Affiliation:MRC Epidemiology Unit, Strangeways Research Laboratory, Worts Causeway, Cambridge CB1 8RN, UK.

Keywords:Complex traits, genetic epidemiology, integrated analysis, statistical and computational geneticsCited by: 3.Chapter 7 (Page no: ) Molecular dissection of complex traits: practice. This chapter discusses the practice of using molecular markers to dissect complex traits and .